Add mayonnaise, hot sauce, melted butter, cayenne pepper, paprika, brown sugar, garlic powder, onion powder, and pickle juice into a bowl. Mix until smooth.

Divide ground beef into eight equal portions. Roll each portion gently into a loose ball. Avoid pressing too tightly because loose meat creates better texture.

Heat a skillet over medium heat. Spread butter on the burger buns. Toast them until golden and slightly crispy for better flavor.

Place a cast iron skillet over high heat. Let it become very hot before cooking. A hot pan creates the crispy crust smash burgers are known for.

Place a beef ball into the skillet. Press firmly with a metal spatula until thin. Season with salt, pepper, garlic powder, and onion powder.

Cook the smashed patty for about two minutes without moving it. This creates crispy edges and a flavorful golden crust.

Flip each patty carefully. Add cheddar cheese on top. Cook for another minute until the cheese melts completely over the juicy beef.

Spread spicy Nashville sauce on the toasted buns. Add two beef patties, lettuce, pickles, and onions. Layer everything carefully for the perfect burger.

Serve the Spicy Nashville Smash Burger immediately while warm. The crispy beef, melted cheese, and spicy sauce taste best when freshly prepared.